Celebrities on GLP-1: The Public Conversation
From Oprah to Serena Williams, public figures are speaking openly about GLP-1 medications. Here\'s the cultural context.
Public Figures Using GLP-1
- Oprah Winfrey — discussed using GLP-1 starting late 2023; has been a major voice in the cultural conversation
- Serena Williams — became a Ro Body Program ambassador in 2025 after discussing postpartum weight-loss use
- Elon Musk — credited Wegovy publicly for a substantial weight loss in 2022
- Tracy Morgan — discussed using Mounjaro/Ozempic on late night TV
- Whoopi Goldberg — confirmed using Mounjaro on The View
- Charles Barkley — discussed Mounjaro use on TNT broadcasts
The Cultural Shift
Public discussion of weight-loss medication has shifted dramatically since 2022. What was once stigmatized has become normalized — partly because GLP-1 medications work, and partly because high-profile figures have been forthright about using them.
The "Ozempic face" media cycle (referring to facial fat loss with rapid GLP-1 weight loss) generated criticism, but the broader trend is acceptance of pharmacological weight management as a legitimate health choice rather than a moral failing or vanity.
Frequently Asked Questions
Why is Serena Williams on GLP-1?
Serena Williams publicly discussed using GLP-1 medication for postpartum weight management. She became a brand spokesperson for telehealth provider Ro's GLP-1 program in 2025.
Is Oprah on GLP-1?
Oprah Winfrey has spoken publicly about using a GLP-1 medication for weight management starting in late 2023. She has discussed the experience and the cultural conversation around GLP-1 weight loss.
Who else uses GLP-1?
Many public figures have discussed GLP-1 use including Elon Musk, Tracy Morgan, Whoopi Goldberg, Charles Barkley, and numerous others. The medication has become culturally normalized in 2024-2026.